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Pharmacodynamics

Research reports on pharmacodynamics from Eli Lilly and Company provide new insights

Published in Blood Weekly, January 1st, 2009

Current study results from the report, 'Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects,' have been published. In this recent report, researchers in the United States conducted a study "To investigate the potential effect of atorvastatin 80 mg/day on the pharmacokinetics and pharmacodynamics of the thienopyridines prasugrel and clopidogrel. Open-label, randomized, crossover, two-arm, parallel-group study."

"Single clinical research center in the United Kingdom. Sixty-nine healthy men aged 18-60 years. Subjects received either a loading dose of prasugrel 60 mg followed by a maintenance dose of 10 mg/day...

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