Published in Blood Weekly, January 8th, 2009
"We and others found that uterine leiomyomas (ULMs) expressed a distinct miRNA signature. In addition, miRNA expression appears to be strongly associated with race and other biomedical factors, such as tumor sizes," wrote J.J. Wei and colleagues, Northwestern University.
The researchers concluded: "Among the most highly dysregulated miRNAs, let-7 miRNAs seem to play a critical role in tumorigenesis of ULMs through negative regulation of some key...
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