World Journal of Gastroenterology
A potential drug for ischemia/reperfusion related liver injury
Published in Blood Weekly, January 8th, 2009
Hepatic injury caused by ischemia/reperfusion (I/R) has been proposed as a key clinical problem associated with liver transplantation and major liver surgery. The production of reactive oxygen species (ROS), including superoxide, hydrogen peroxide, and hydroxyl radical, has been demonstrated in reperfusion injury. Resveratrol has been reported to have several biologic effects such as a potent antioxidative effect via prevention of lipid peroxidation.
A research team led by Ercan Gedik from Turkey evaluated the possible protective effect of resveratrol against I/R-induced hepatic injury, using biochemical and histological parameters. This will be published on December...
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Source: Blood Weekly (2009-01-08)
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