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Necrotizing Fasciitis

Research from Nagasaki University yields new data on necrotizing fasciitis

Published in Blood Weekly, January 22nd, 2009

"Herein, we describe five patients with necrotizing fasciitis (NF) who had variable outcomes and clinical manifestations. At the onset, all patients exhibited purpura with or without blister and ulceration accompanied by severe pain and tenderness in the affected skin," scientists in Sakamoto, Japan report.

"Out of five patients, three lacked inflammatory signs such as redness and heat, and two of the three patients showed fulminant progression and died despite intensive treatments including surgical debridement, antimicrobial therapy, close monitoring and physiological support. Tissue specimens from the patients without skin inflammatory signs showed mild neutrophil...

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