Published in Blood Weekly, January 29th, 2009
"Here, we show that HPV-16 E7 induces an increased formation of alternative lengthening of telomeres (AI,T)-associated promyelocytic leukemia bodies (APBs) in early passage primary human keratinocytes as well as HPV-negative tumor cells. This activity was found to require sequences of HPV-16 E7 involved in degradation of the...
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