Published in Blood Weekly, February 5th, 2009
"This pDNA vector combines a scaffold/matrix attachment region (S/MAR) with a human liver-specific promoter (alpha 1-antitrypsin (AAT)) in such a way that long-term expression is enabled in murine liver following hydrodynamic injection. Long-term expression is demonstrated by monitoring the longitudinal luciferase expression profile for up to 6 months by means of in situ...
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