University of Rochester Medical Center

Researchers detail how aging undermines bone healing

Published in Blood Weekly, February 5th, 2009

Researchers have unraveled crucial details of how aging causes broken bones to heal slowly, or not at all, according to study results published in the Journal of Bone and Mineral Research. The research team also successfully conducted preclinical tests on a potential new class of treatments designed to "rescue" healing capability lost to aging.

In the worst cases, an age-related delay in healing keeps the two sides of a fractured bone from ever rejoining (non-union), leaving many confined to wheelchairs, unable to walk or to live independently. Of the estimated 5.6 million fractures in the United States each year, between five and ten percent (up to 560,000) will heal...

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Source: Blood Weekly (2009-02-05)

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