Transfusion Medicine
Reports summarize transfusion medicine research from Harvard University
Published in Blood Weekly, February 19th, 2009
According to recent research published in the journal Anesthesiology, "Hemoglobin-based oxygen-carrying solutions (HBOC) provide emergency alternatives to blood transfusion to carry oxygen to tissues without the risks of disease transmission or transfusion reaction. Two primary concerns hampering the clinical acceptance of acellular HBOC are the occurrence of systemic and pulmonary vasoconstriction and the maintenance of the heme-iron in the reduced state (Fe+2)."
"We recently demonstrated that pretreatment with inhaled nitric oxide prevents the systemic hypertension Induced by HBOC-201 (polymerized bovine hemoglobin) Infusion in awake mice and sheep without...
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Source: Blood Weekly (2009-02-19)
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