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Fibrinolysis

Studies from H.Y. He et al have provided new data on fibrinolysis

Published in Blood Weekly, February 19th, 2009

" Sepsis induced acute lung injury (ALI) as a common syndrome in clinical practice has a high mortality. Recombinant human activated protein C (APC) can significantly reduce the mortality of patients with severe sepsis," scientists in Beijing, People's Republic of China report.

"Several studies have implicated that APC may be protective in ALI. Twenty-one rabbits were operatively prepared and randomly divided into sham, control, or APC groups (n=7 in each group). After a tracheotomy had been performed, ALI was produced in the control and APC groups by infusion of Escherichia coli endotoxin 100 mu g/kg per hour intravenously for 1 hour. The sham group received only the...

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