Sepsis

Data on bone research detailed by R. Boregowda and co-authors

Published in Blood Weekly, February 26th, 2009

"Fibrillins 1, 2 and 3 make up a family of genes that encode large, cysteine-rich extracellular matrix glycoproteins found in connective tissues, lung, blood vessels and other extensible tissues. Fibrillins I and 2 have both overlapping as well as separate distributions in human embryonic and adult tissues," scientists writing in the journal Matrix Biology report.

"Fibrillin-containing microfibrils are known to modulate morphogenetic events by proper targeting of growth factors to the extracellular matrix. Mutation of the fibrillin-2 gene causes a genetic disorder, congenital contractural arachnodactyly (CCA), that results in flexion contractures. Previously, we...

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Source: Blood Weekly (2009-02-26)

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