Lymphoma
Studies from Mayo Clinic update current data on lymphoma
Published in Blood Weekly, March 5th, 2009
According to recent research published in the journal Blood, "We conducted comprehensive gene expression profiling (GEP) of primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma (n=33) and compared the results to GEP of other B-and T-cell lymphomas and normal lymphocytes to identify novel markers and deregulated pathways. MALT has a prominent T-cell signature and a marginal zone/memory B-cell profile."
"Four novel transcripts were specifically overexpressed in MALT, and 2 of these, MMP7 and SIGLEC6, were validated at the protein level. GEP also revealed distinct molecular subsets in MALT. One subset, characterized by MALT1 translocations, showed...
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Source: Blood Weekly (2009-03-05)
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