Thrombosis

New thrombosis findings from Leiden University published

Published in Blood Weekly, March 5th, 2009

"Protein C is an important inhibitor of blood coagulation. We investigated the effect of two polymorphisms within the promoter region of the protein C gene (C/T at position 2405 and A/G at position 2418) on risk of venous thrombosis and on plasma protein C levels," scientists writing in the journal Thrombosis and Haemostasis report.

"In addition the combined effect of the two polymorphisms with factor V Leiden and oral contraceptive use was investigated. Previous studies on these polymorphisms were small and were not able to investigate synergistic effects. In the Multiple Environmental and Genetic Assessment of risk factors for venous thrombosis (MEGA study),...

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Source: Blood Weekly (2009-03-05)

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