Hepatocellular Cancer

New hepatocellular cancer research from Virginia Commonwealth University discussed

Published in Blood Weekly, March 19th, 2009

"Des-gamma-carboxy prothrombin (DCP) and Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3) are surveillance markers used to detect hepatocellular carcinoma (HCC) in Japan. This study evaluated their utility, alone or in combination, in a North American population," researchers in the United States report.

"Patients with hepatitis C virus-related cirrhosis were followed up prospectively for 2 years. Of 372 patients, HCC developed in 34 of 298 who were free of HCC at entry. The overall sensitivity, specificity, and positive and negative predictive values for only AFP (>20 ng/mL) were 61%, 71%, 34%, and 88%, respectively; for only AFP-L3% (>...

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Source: Blood Weekly (2009-03-19)

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