Published in Blood Weekly, March 19th, 2009
"In this study, the function of macrophage PPAR and LXR in Th1-biased C57BL/6 mice was tested using a bone marrow transplantation approach with PPAR gamma(-/-), PPAR delta(-/-), PPAR gamma delta(-/-), and LXR alpha beta(-/-) cells. Despite their inhibitory effects on inflammatory gene expression, loss of PPARs or LXRs in macrophages...
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