Sepsis

Charles University, Medical Department details research in sepsis

Published in Blood Weekly, March 26th, 2009

According to a study from Plzen, Czech Republic, "The role of haemofiltration as an adjunctive treatment of sepsis remains a contentious issue. To address the role of dose and to explore the biological effects of haemofiltration we compared the effects of standard and high-volume haemofiltration (HVHF) in a peritonitis-induced model of porcine septic shock."

"Randomized, controlled experimental study. Twenty-one anesthetized and mechanically ventilated pigs. After 12 h of hyperdynamic peritonitis, animals were randomized to receive either supportive treatment (Control, n = 7) or standard haemofiltration (HF 35 ml/kg per h, n = 7) or HVHF (100 ml/kg per hour, n = 7)....

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Source: Blood Weekly (2009-03-26)

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