Carcinoma

Recent studies by A.P.D. Demasi and co-authors add new data to carcinoma findings

Published in Blood Weekly, April 9th, 2009

"Carcinoma ex pleomorphic adenoma is a rare salivary gland malignancy. It constitutes an important model for the study of carcinogenesis, as it can display the tumor in different stages of progression, from benign pleomorphic adenoma to frankly invasive carcinoma," scientists in Campinas, Brazil report.

"Growth signaling pathways undergo continuous activation in human tumors, commonly as a consequence of the overexpression of ligands and receptors such as platelet-derived growth factor and platelet-derived growth factor receptor. Hydrogen peroxide is produced after platelet-derived growth factor receptor activation, and it is essential for the sequential phosphorylation...

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Source: Blood Weekly (2009-04-09)

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