University of Utah Health Sciences
Premature newborns lack 'death NET' to fight sepsis
Published in Blood Weekly, April 9th, 2009
When locked in mortal combat with infection, some mature white blood cells have a formidable weapon: they literally cast a DNA net—called a neutrophil extracellular trap (NET)—that captures and kills bacteria that invade the human body. But the ability to form this "death" NET is missing in the white blood cells of newborn infants, born either at term or prematurely, and that, in part, may explain why millions of newborns worldwide are at higher risk for a potentially deadly blood infection, University of Utah medical researchers have discovered.
The finding, published online in the journal Blood, is important because it provides insight into defects in the body's...
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Source: Blood Weekly (2009-04-09)
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