Life Sciences
New life sciences research from University of Medicine and Dentistry of New Jersey, Cancer Institute of New Jersey described
Published in Blood Weekly, April 16th, 2009
Data detailed in 'Targeted deletion of Nm23/nucleoside diphosphate kinase A and B reveals their requirement for definitive erythropoiesis in the mouse embryo' have been presented. According to recent research published in the journal Developmental Dynamics, "The ubiquitously expressed nucleoside diphosphate kinases (Nm23/NDPK/Awd) are a large family of multifunctional enzymes implicated in nucleic acid metabolism and in normal and abnormal development. Here, we describe the generation and characterization of NDPK A-and B-deficient (Nme1(-/-)/Nme2(-/-)) mice in which >95% of the enzyme activity is eliminated."
"These mice are undersized, die perinatally, and...
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Source: Blood Weekly (2009-04-16)
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