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Bronchopulmonary Dysplasia

New bronchopulmonary dysplasia study findings have been published by scientists at University of Texas

Published in Blood Weekly, April 23rd, 2009

"Nitric oxide (NO) plays an important role in lung development and perinatal lung function, and pulmonary NO synthases (NOS) are decreased in bronchopulmonary dysplasia (BPD) following preterm birth. Fetal estradiol levels increase during late gestation and estradiol up-regulates NOS, suggesting that after preterm birth estradiol deprivation causes attenuated lung NOS resulting in impaired pulmonary function," researchers in the United States report.

"To test the effects of postnatal estradiol administration in a primate model of BPD over 14 days after delivery at 125 days of gestation (term = 185 cl). Cardiopulmonary function was assessed by echocardiography and whole...

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