Bone Research

Reports on bone research findings from University of Florence provide new insights

Published in Blood Weekly, May 21st, 2009

According to recent research from Florence, Italy, "Absolute activity evaluation is fundamental for internal radionuclide dosimetry when patient-specific therapy optimization is wanted. Often, quantification is attempted with 3D SPECT image based (IB) methods, but the true concentration values can be underestimated due to the partial volume effect (PVE)."

"This is especially true when small diffuse lesions are present. In this paper, we describe a 3D region of interest (ROI) based quantification method (LS-ROI), which estimates the ROI concentration values directly from the projection data acquired in the tomographic scan once ROIs have been segmented on a CT and/or a...

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Source: Blood Weekly (2009-05-21)

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