Left Ventricular Hypertrophy

Research conducted at Nagoya University has provided new information about left ventricular hypertrophy

Published in Blood Weekly, May 21st, 2009

According to recent research published in the Circulation Journal, "Experimental studies have reported that allopurinol protects hypertensive rats from left ventricular hypertrophy (LVH) with negligible effects on blood pressure (BP). Uric acid (UA) was thought to induce cardiomyocyte growth and interstitial fibrosis of the heart, partly via activation of the renin-angiotensin system."

"In the present study, the relationship between serum UA levels and electrocardiographically-diagnosed LVH (ECG-LVH) was examined in Japanese men not taking medication for hypertension (HTN), which could confound the association. A total of 3,305 male workers aged 35-66 years (mean...

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Source: Blood Weekly (2009-05-21)

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