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Veno-occlusive Disease

Studies from University of Basel further understanding of veno-occlusive disease

Published in Blood Weekly, May 21st, 2009

"Haematopoietic stem cell transplantation is Currently the only Curative option for many haematological malignancies, but is characterized by a wide spectrum of complications, including haemostatic changes. Bleeding and thrombotic events occur in the early and late phases after transplantation," investigators in Basel, Switzerland report.

"In the early phase, thrombotic events have a variable clinical picture and present either as venous thrombosis, mainly at the site of central venous lines, veno-occlusive disease (also known as sinusoid Occlusion syndrome) or transplant-associated microangiopathy. The latter two Occur in the context of an acute graft-vs-host reaction,...

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