Stem Cell Research
Research on stem cell research described by I. Prigione and colleagues
Published in Blood Weekly, June 4th, 2009
According to recent research from Genoa, Italy, "The immunomodulatory activities of human mesenchymal stem cells (MSCs) provide a rational basis for their application in the treatment of immune-mediated diseases, such as graft versus host disease and multiple sclerosis. The effects of MSCs on invariant natural killer T (iNKT) and gamma delta T cells, both involved in the pathogenesis of autoimmune diseases, are unknown."
"Here, we investigated the effects of MSCs on in vitro expansion of these unconventional T-cell populations. MSCs inhibited iNKT (V alpha 24(+)V beta 11(+)) and gamma delta T (V delta 2(+)) cell expansion from peripheral blood mononuclear cells in both...
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Source: Blood Weekly (2009-06-04)
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