Chronic Lymphocytic Leukemia

Studies from G. Perezchacon and co-researchers yield new data on chronic lymphocytic leukemia

Published in Blood Weekly, June 11th, 2009

"In the last few years, it has been suggested that the involvement of human leukocyte antigen-G (HLA-G) in several tumoral processes and its likely participation as a factor of immune tolerance in malignant cells," scientists in Madrid, Spain report.

"Recently, positive HLA-G surface expression has been associated with a poor prognosis in a small group of patients with B-cell chronic lymphocytic leukemia (B-CLL), a lymphoproliferative disorder characterized by a heterogeneous clinical course. In the present work, 169 patients suffering from B-CLL were analyzed for the expression of HLA-G by flow cytometry in order to verify its prognostic value in a larger cohort,"...

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Source: Blood Weekly (2009-06-11)

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