Inflammation

Data on inflammation detailed by researchers at University of Wisconsin

Published in Blood Weekly, June 11th, 2009

According to a study from the United States, "MicroRNAs (miRNAs) are similar to 22 nucleotides long, noncoding RNAs that control cellular function by either degrading mRNAs or arresting their translation. To understand their functional significance in ischemic pathophysiology, we profiled miRNAs in adult rat brain as a function of reperfusion time after transient middle cerebral artery occlusion."

"Of the 238 miRNAs evaluated, 8 showed increased and 12 showed decreased expression at least at 4 out of 5 reperfusion time points studied between 3 h and 3 days compared with sham. Of those, 17 showed >5 fold change. Bioinformatics analysis indicated a correlation between...

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Source: Blood Weekly (2009-06-11)

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