Knee Arthroplasty
New cancer study findings recently were reported by researchers at University of Texas
Published in Blood Weekly, June 11th, 2009
According to a study from the United States, "In order to explore the apoptotic and anti-tumor activities of metallo-salens, we synthesized several Mn(III)-salen derivatives (compds. 1-9) and analyzed their effects on cultured human cancer and non-cancer cells. Our results demonstrated that Mn(III)-salen derivatives affect cell viability, induce nuclear condensation and fragmentation in breast cancer cells (MCF7)."
"Mn(III)-salen derivatives also induced caspase-3/7 activation and release of cytochrome-c from the mitochondria to cytosol suggesting that Mn(Ill)-salen derivatives induce apoptosis in human cells via mitochondrial pathway. Importantly, the nature of the...
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Source: Blood Weekly (2009-06-11)
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