Sepsis

New sepsis study findings recently were published by M.F. Osuchowski and co-researchers

Published in Blood Weekly, June 11th, 2009

According to recent research from Vienna, Austria, "This study examined the effectiveness of prospective stratification to identify and target high-dose glucocorticoid therapy for subjects developing lethal sepsis. Prospective, randomized, laboratory-controlled experiment."

"Adult female outbred CD-1 mice. Mice (n = 88) were subjected to sepsis induced by cecal ligation and puncture (CLP). Mice were prospectively divided into two groups, predicted to die (P-DIE) or predicted to live (P-LIVE), based on plasma levels of interleukin (IL)-6 obtained 6 hours after CLP. Following stratification, dexamethasone (DEX, 2.5 mg/kg, two doses) was administered to half the animals in...

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Source: Blood Weekly (2009-06-11)

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