Sepsis

University of Munich reports research in sepsis

Published in Blood Weekly, June 11th, 2009

"Purpose of review Main problems of critical illness and sepsis are an altered oxygen distribution and microvascular dysfunction linked to tissue oedema. This review seeks to analyse the role of the endothelial glycocalyx in this context," investigators in Munich, Germany report.

"Recent findings The presence of vascular leakage is typically associated with interstitial oedema, arterial hypotension, hypovolaemia and often a bad outcome in patients with systemic inflammation. Early goal-directed therapy provides significant benefits in severe sepsis and septic shock, but is mostly aimed at improving macrohaemodynamics. Recent data suggest that microcirculation also...

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Source: Blood Weekly (2009-06-11)

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