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Tissue Engineering

Researchers from University of Milan report on findings in tissue engineering

Published in Blood Weekly, June 11th, 2009

According to recent research from Milan, Italy, "Skeletal muscles of subjects with advanced cancer undergo progressive wasting, referred to as cachexia. Cachexia is an important area for medical research because strategies proposed until now have yielded little benefit."

"We have recently identified necdin as a key player in fetal and postnatal physiological myogenesis and in muscle regeneration. Here we show that necdin is selectively expressed in muscles of cachetic mice and prove that its expression is causally linked to a protective response of the tissue against tumor-induced wasting, inhibition of myogenic differentiation and fiber regeneration," wrote C. Sciorati...

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