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Tissue Engineering

Studies from University of Tubingen in the area of tissue engineering published

Published in Blood Weekly, June 11th, 2009

According to a study from Tubingen, Germany, "Microtraumata often lead to articular cartilage lesions. Due to the bradytrophic character of hyaline cartilage, these lesions are hardly repaired by the organism."

"Autologous chondrocyte implantation (ACI) was established for restoring isolated structural cartilage defects in knee joints. However, results are not always convincing. Human chondrocytes from patients undergoing total knee arthroplasty were cultured in monolayer followed by condensing single chondrocytes to spheroids (chondrospheres (R)). The integrative capacity of chondrospheres was examined by implanting them into lesions in human articular cartilage...

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