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Chronic Lymphocytic Leukemia Genetics

Data on chronic lymphocytic leukemia genetics discussed by researchers at Gunma University

Published in Blood Weekly, June 11th, 2009

Current study results from the report, 'Characterization of immunoglobulin heavy and light chain gene expression in chronic lymphocytic leukemia and related disorders,' have been published. According to recent research from Gunma, Japan, "The incidence of chronic lymphocytic leukemia is low in the Japanese population compared with populations in western countries, suggesting a role for genetic factors in the occurrence of this disease. We have previously shown that chronic lymphocytic leukemia in Japan rarely expresses the immunoglobulin heavy chain variable region (IGHV) 1-69 gene (1 out of 43 patients, 2.3%), which is a gene most commonly expressed in chronic lymphocytic leukemia cases...

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