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Research from Dankook University, Department of Physiology in the area of life sciences published

Published in Blood Weekly, June 11th, 2009

Scientists discuss in 'Cytolytic assessment of hyperacute rejection and production of nuclear transfer embryos using hCD46-transgenic porcine embryonic germ cells' new findings in life sciences. "Human complement regulatory protein hCD46 may reduce the hyperacute rejection (HAR) in pig-to-human xenotransplantation. In this study, an hCD46 gene was introduced into porcine embryonic germ (EG) cells," scientists in Korea report.

"Treatment of human serum did not affect the survival of hCD46-transgenic EG cells, whereas the treatment significantly reduced the survival of non-transgenic EG cells (p <0.01). The transgenic EG cells presumably capable of alleviating HAR were...

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