Bioluminescence

Study results from S.H. Li et al provide new insights into bioluminescence

Published in Blood Weekly, June 11th, 2009

"Cell therapy improved cardiac function after a myocardial infarction in several preclinical studies; however, the functional benefits were limited in the initial clinical trials, perhaps because of inadequate cell engraftment. We used noninvasive molecular imaging to compare the distribution and myocardial retention of cells implanted by using clinical delivery routes," scientists in Toronto, Canada report.

"Bone marrow stromal cells isolated from male rats and transfected with a firefly luciferase reporter gene were injected by using 3 increasingly invasive techniques (ie, intravenous, intra-aortic, and intramyocardial) into female rats 3 or 28 days after coronary...

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Source: Blood Weekly (2009-06-11)

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