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Bone Marrow Transplantation
New bone marrow transplantation study findings have been reported from Kyoto University
June 18th, 2009
"We evaluated the efficacy of a post-grafting immunosuppressive regimen consisting of tacrolimus, methotrexate, and mycophenolate mofetil (MMF) in 21 adults (median age, 55 years) with poor-risk hematologic malignancy who underwent unrelated bone marrow transplantation after fludarabine-based reduced-intensity conditioning (RIC). In combination with intravenous tacrolimus and minidose methotrexate (5 mg/m(2) on days 1, 3, and 6), MMF was orally administered at 30 mg/kg daily in three divided doses between days 7 and 27," investigators in Kyoto, Japan report. "All patients achieved neutrophil recovery with donor-type chimerism at a median of 19 days (range, 13-35)....
Source: Blood Weekly (2009-06-18)
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