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Follicular Lymphoma
Research on follicular lymphoma published by M. Mollejo et al
June 18th, 2009
According to a study from Madrid, Spain, "The spleen is frequently involved in B-cell lymphomas other than splenic marginal zone lymhoma. Here we describe a series of follicular lymphoma (FL) cases diagnosed in the spleen, consisting of 32 patients who presented clinically with splenomegaly, and slight or no peripheral lymphadenopathy." "The splenic specimen had a micronodular pattern, germinal center cytologic composition, and frequent presence of marginal zone-like cells at the periphery of the nodules. Twenty cases showed absence or only partial/weak bcl2 protein expression, and 12 cases had homogeneous and strong positive bcl2 expression. The incidences of...
Source: Blood Weekly (2009-06-18)
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