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Burkitt Lymphoma

Reports summarize Burkitt lymphoma study results from I. Molinaprivado and co-researchers

Published in Blood Weekly, June 25th, 2009

"Current treatments of sporadic Burkitt's lymphoma (sBL) are associated with severe toxicities. A better understanding of sBL formation would facilitate development of less toxic therapies," scientists writing in the journal Cancer Research report.

"The etiology of sBL remains, however, largely unknown, C-MYC up-regulation being the only lesion known to occur in all sBL cases. Several studies examining the role of C-MYC in the pathogenesis of BL have concluded that C-MYC translocation is not the only critical event and that additional unidentified factors are expected to be involved in the formation of this tumor. We herein report that a gene distinct from C-MYC,...

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