Stem Cell Research

Researchers at Pennsylvania State University, Medical Department publish new data on stem cell research

Published in Blood Weekly, July 9th, 2009

"Human embryonic stem cells (hESCs) are characterized by their immortality and pluripotency. Human mesenchymal stem cells (hMSC), on the other hand, have limited self-renewal and differentiation capabilities," scientists writing in the journal Stem Cells and Development report.

"The underlying molecular differences that account for this characteristic self-renewal and plasticity are, however, poorly understood. This study reports a nuclear proteomic analysis of human embryonic and bone marrow-derived mesenchymal stem cells. Our proteomic screen highlighted a 5-fold difference in the expression of Reptin52. We show, using two-dimensional difference gel...

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Source: Blood Weekly (2009-07-09)

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