Published in Blood Weekly, July 9th, 2009
The link between inherited variants in the CEBPA gene and the familial form of acute myeloid leukemia (AML) was first described in the New England Journal of Medicine in 2004. This relationship has subsequently been confirmed in several published reports. Almost all patients found to have inherited CEBPA mutations have had leukemia. Therefore, germline CEBPA mutations appear to predict the...
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