University of Texas Medical Branch at Galveston

Scientists block Ebola infection in cell-culture experiments

Published in Blood Weekly, July 9th, 2009

Researchers at the University of Texas Medical Branch at Galveston have discovered two biochemical pathways that the Ebola virus relies on to infect cells. Using substances that block the activation of those pathways, they've prevented Ebola infection in cell culture experiments — potentially providing a critical early step in developing the first successful therapy for the deadly virus.

Ebola inflicts severe and often fatal hemorrhagic fever on its victims, producing 90 percent mortality rates in some outbreaks. No vaccine exists for the virus, and it is considered a high-risk agent for bioterrorism. Natural Ebola outbreaks strike periodically, often with devastating...

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Source: Blood Weekly (2009-07-09)

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