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Follicular Lymphoma Immunology

Research from Okayama University provides new data about follicular lymphoma immunology

Published in Blood Weekly, July 16th, 2009

Researchers detail in 'Duodenal and nodal follicular lymphomas are distinct: the former lacks activation-induced cytidine deaminase and follicular dendritic cells despite ongoing somatic hypermutations,' new data in follicular lymphoma. According to recent research published in the journal Modern Pathology, "Although most follicular lymphomas are believed to be of nodal origin, they sometimes originate from the duodenum. We have reported that the latter differ from nodal follicular lymphomas in having lower clinical stages and uniformly low histological grades, along with variable region of immunoglobulin heavy chain gene (VH) usage that is more similar to mucosa-associated lymphoid...

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