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Pharmacokinetics

Reports from J. Jiang and co-researchers add new data to research in pharmacokinetics

Published in Blood Weekly, July 23rd, 2009

"The primary aim of this study was to investigate the pharmacokinetics and safety of daily oral doses of olmesartan medoxomil administered to healthy Chinese subjects for 7 days. All 14 subjects (8 males/6 females) received a single dose of 20 mg olmesartan medoxomil and followed by multiple oral doses of 20 mg olmesartan medoxomil once daily for 7 days," scientists in Beijing, People's Republic of China report.

"Blood and urine samples were obtained for a 48-h pharmacokinetic evaluation on two PK days (Day 1 and Day 9). The systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate were determined at the scheduled time for safety evaluation. The...

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