Alpha-thalassemia
Studies from Chiang Mai University, Medical Department further understanding of alpha-thalassemia
Published in Blood Weekly, August 13th, 2009
In this recent study, researchers in Chiang Mai, Thailand conducted a study "To determine the sensitivity and specificity of middle cerebral artery peak systolic velocity (MCA-PSV) in mid-pregnancy for the identification of homozygous alpha-thalassemia-1 (hemoglobin (Hb) Bart's disease) in fetuses at risk of the disease. A total of 88 pregnancies (91 fetuses) at risk of Hb Bart's disease and undergoing MCA-PSV measurement before cordocentesis at 18-22 weeks of gestation were recruited into the study."
"Definitive diagnosis was made using the gold standard technique of Hb typing by high-performance liquid chromatography. The mean +/- SD age of the 88 pregnant women...
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Source: Blood Weekly (2009-08-13)
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