Epstein-Barr Virus

University of Ulm reports research in Epstein-Barr virus

Published in Blood Weekly, August 20th, 2009

"Atherosclerosis is characterized by a complex immune response in the vessel wall, involving both inflammation and autoinumme processes. Epstein-Barr virus-induced gene 3 (Ebi3) is a member of the interleukin (IL)-12 heterodimeric cytokine family, which has important immunomodulatory functions," scientists writing in the American Journal of Pathology report.

"To date, little is known about the role of Ebi3 in vascular disease. We examined the expression of Ebi3 in human atheromatous lesions and analyzed its transcriptional regulation in vascular cells. The in situ expression of Ebi3 in human endarterectomy specimens was analyzed by immunohistochemistry. In these...

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Source: Blood Weekly (2009-08-20)

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