Stem Cell Research

Investigators at Harvard University release new data on stem cell research

Published in Blood Weekly, August 20th, 2009

"of review Rho GTPases are key molecular switches controlling the transduction of external signals to cytoplasmic and nuclear effectors. In the last few years, the development of genetic and pharmacological tools has allowed a more precise definition of the specific roles of Rho GTPases in hematopoietic stem cells (HSCs) and progeny of these cells," researchers in the United States report.

"Rho GTPases are now known to be crucial in HSCs response to hematopoietic microenvironment cues. This article will review the known HSC functions, which are regulated by Rho GTPases. Recent findings This review analyzes the latest data on how different Rho GTPases control adhesion,...

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Source: Blood Weekly (2009-08-20)

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