Enzyme Research
Study data from University of Cincinnati, Division of Internal Medicine update knowledge of enzyme research
Published in Blood Weekly, August 27th, 2009
Research findings, 'Aminophospholipid translocase and phospholipid scramblase activities in sickle erythrocyte subpopulations,' are discussed in a new report. "Phosphatidylserine (PS) externalization may contribute to Sickle Cell Disease (SCD) characteristics including thrombogenesis, endothelial adhesion and shortened red blood cell (RBC) lifespan. Aminophospholipid translocase (APLT) returns externalized PS to the inner membrane, and phospholipid scramblase (PLSCR) equilibrates phospholipids (PL) across the membrane," investigators in the United States report.
"APLT inhibition and PLSCR activation appear to be important for PS externalization. We examined...
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Source: Blood Weekly (2009-08-27)
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