Xenotransplantion

College of Medicine reports research in xenotransplantion

Published in Blood Weekly, September 3rd, 2009

"Identification of transplanted human cells in mouse models is important for studying the biology and therapeutic potential of stem/progenitor cells. As stem/progenitor cells are often transplanted in low numbers, detection of cell engraftment requires sensitive tools," scientists in the United States report.

"Probes for single copy genes, as well as repetitive genetic elements are available for detecting transplanted cells, although their value relative to one another had not been defined. We examined whether human sequences in chimeric mice could be measured with quantitative real-time polymerase chain reactions for Charcot-Marie-Tooth disease, type 1 repeat element,...

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Source: Blood Weekly (2009-09-03)

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