Life Sciences
Studies from E. Breous and co-authors have provided new information about life sciences
Published in Blood Weekly, September 24th, 2009
According to a study from the United States, "The mechanisms of tolerance in the liver that limit susceptibility to food allergy and that mediate the acceptance of liver transplants, even with a complete major histocompatibility complex (MHC) mismatch, remain poorly defined. Here we report that in a model of liver-directed gene transfer, cytotoxic T lymphocyte (CTL) responses to non-self antigens are controlled by hepatic regulatory T cells (Tregs) that secrete the immunosuppressive cytokine interleukin (IL)-10 in response to the antigen."
"In addition, Kupffer cells (KCs), normally thought to initiate immune responses, are rendered tolerogenic in this context. The...
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Source: Blood Weekly (2009-09-24)
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