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Cardiomyopathy

Research on cardiomyopathy reported by J.E. Saffitz et al

Published in Blood Weekly, October 1st, 2009

"Arrhythmogenic cardiomyopathy is characterized by a high incidence of ventricular tachyarrhythmias, which often occur early in the disease before significant ventricular remodeling or contractile dysfunction develops. Arrhythmogenic right ventricular cardiomyopathy (ARVC) is the most common clinicopathological form of this group of diseases, but left ventricular and biventricular forms have been increasingly recognized," investigators in the United States report.

"Approximately a third of patients with arrhythmogenic cardiomyopathy have mutations in genes encoding proteins of the desmosome, cell-to-cell adhesion organelles Located at cardiac myocyte intercalated disks....

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