Ischemia

New ischemia study findings recently were published by researchers at University of Jena

Published in Blood Weekly, October 15th, 2009

"Acute ischemia is a well-known inductor of extracellular matrix (ECM) remodeling, which leads to the development of congestive heart failure and is associated with left ventricular dilatation. Here we investigate the timecourse of ECM processing with release of endostatin (ES) and other low-molecular-weight fragments during early ischemia-reperfusion of the heart," researchers in Jena, Germany report.

"In this blinded study, 30 pigs were randomized to 60 min of global myocardial ischemia at either 4 or 37A degrees C or served as control. Five transmyocardial tissue samples were collected at baseline and after ischemia within 150 min of reperfusion. Collagen XVIII...

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Source: Blood Weekly (2009-10-15)

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