Enzyme Research

New enzyme research from University of Cambridge, Cambridge Institute for Medical Research discussed

Published in Blood Weekly, October 15th, 2009

Investigators publish new data in the report 'Molecular basis of thrombomodulin activation of slow thrombin.' According to a study from Cambridge, the United Kingdom, "Coagulation is a highly regulated process where the ability to prevent blood loss after injury is balanced against the maintenance of blood fluidity. Thrombin is at the center of this balancing act."

"It is the critical enzyme for producing and stabilizing a clot, but when complexed with thrombomodulin ™ it is converted to a powerful anticoagulant. Another cofactor that may play a role in determining thrombin function is the monovalent cation Na(+). Its apparent affinity suggests that half of the...

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Source: Blood Weekly (2009-10-15)

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